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Short answer: the safest picks — S: Charge Rifle, Chain Shotgun, Persona Zeushammer, Monosword. A: Assault Rifle, Heavy SMG, LMG, Longsword, Plasmasword. Everything else is niche or vendor trash.

Ranged weapons

TierWeaponsWhy
SCharge Rifle, Chain ShotgunBest sustained DPS — charge rifle dominates at range, chain shotgun deletes anything close
AAssault Rifle, Heavy SMG, LMG, Sniper RifleReliable mid-game backbone; LMG for crowds, sniper for picks
BBolt-Action Rifle, Pump Shotgun, Machine PistolSolid early craftable stops
CRevolver, Autopistol, Short Bow, Great BowStarter gear — upgrade out of them

Melee weapons

TierWeaponsWhy
SPersona Zeushammer, MonoswordZeushammer's EMP shuts down mechs; monosword cuts through anything
APlasmasword, Longsword, GladiusPlasmasword burns, quality steel blades are the dependable standard
BMace, Spear, War HammerBlunt options for downing pawns you want alive
CKnife, Club, IkwaTribal-era stops
Quality beats tier: a legendary longsword outperforms a poor monosword. Check the weapon card's actual DPS and AP before swapping.

Colony rules of thumb

Early game

Bolt-action rifles and pump shotguns are cheap and effective — don't overinvest in melee yet.

Mid game

Assault rifles and heavy SMGs bridge you to charge weapons; one LMG helps with packs.

Late game

Charge rifles on shooters, zeushammers on melee — EMP mechs, cut the rest.

Situationals

Grenades for sieges, EMP launchers vs mech clusters, incendiary only if you like collateral damage.

FAQ

What's the single best gun in RimWorld?

Charge rifle for ranged DPS, chain shotgun for point-blank — most colonies run a mix of both.

Best melee weapon against mechs?

Persona zeushammer — its EMP effect disables mechanoids, which is why melee hunters carry it even on ranged pawns' backups.

Is the monosword still top tier?

Yes — highest single-target melee DPS with armor penetration. Zeushammer wins specifically vs mechs.